Osobe s invaliditetom sposobne su za zapošljavanje, ali ih poslodavci ne zapošljavaju dovoljno. Te činjenice znatno utječu na njihovu kvalitetu života, kao i na samopercepciju osobe. Načelo supsidijarnosti u sklopu primijenjene bioetike može izazvati pomake na društvenoj razini i pomoći u rješavanju tog problema. Demografski su čimbenici poražavajući za kvalitetu života i rada osoba s invaliditetom. Negativni učinci krize morala u društvu upućuju na nesklad između materijalnog i duhovnog, moralnog i prevladavajućeg vrijednosnog sustava društva i pogađaju najranjivije skupine, a to su osobe s invaliditetom, i to u njihovu školovanju, radu i osobnom životu. Zajednička sinergija bioetike kao sveobuhvatnog teorijskog korektiva i učinkovite prakse jest putovanje prema autonomiji osobe s invaliditetom. Javnost mora pomoći i dopustiti osobama s invaliditetom da budu percipirane kao ravnopravni članovi društva. Pozitivan ishod nije ostvariv bez primjene načela supsidijarnosti.; People with disabilities are capable of employment, but employers do not employ them enough. These facts have a significant influence on their quality of life as well as their self-perception. The principle of subsidiarity as part of applied bioethics can cause social changes and help address this problem. Demographic factors are devastating to the quality of life and work of people with disabilities. The negative effects of the moral crisis in the society point to the disagreement between the material and spiritual, moral and prevailing value system of society and affect the most vulnerable groups, namely persons with disabilities, in their education, work and personal life. Joint synergy between bioethics and practice is a journey towards the autonomy of people with disabilities. The public has to help and allow people with disabilities to be perceived as equal members of society. A positive outcome cannot be achieved without applying the principle of subsidiarity.