The rapid spread of porcine epidemic diarrhea (PED) in different countries in a short time while and the significant economic damage caused by it were important reasons for conducting long-term monitoring studies in Ukraine. PED monitoring researches conduct carry out during 2014-2018 using RT-PCR and ELISA showed the presence of infection in 14 (66.67%) of 21 examined regions of Ukraine. For the period 2014- 2018, the proportion of PED cases rate was the lowest in 2017 (1.76%) and the highest in 2016 (48.03%). Over the entire period, the percentage seropositive animals progressively decreased to a seronegative status indicator defined in sows in 2018. The results of determination of the virulence of 40 strains of PED virus from different regions of Ukraine using the RT-PCR method proved the circulation of highly virulent strains. The phylogenetic analysis demonstrated that the endemic strain of PED virus is included in the cluster of North American strains and the Chinese strains. Important is the fact that it is not included in the group of European low- virulent S-INDEL strains. Thus, the obtained data indicate a high probability that the PED virus was introduced into Ukraine from the territory of the Asian continent or the United States of America (a high probability that the PED virus was translocated from the territory of the Asian continent or the United States of America into Ukraine).; Brzo širenje epidemijskog proljeva svinja (PED) u različitim zemljama tijekom kratkog razdoblja, koje je rezultiralo znatnom ekonomskom štetom, potaknulo je potrebu za dugoročnim studijama praćenja u Ukrajini. Praćenje PED uporabom RT- PCR i ELISA u razdoblju 2014.-2018. godine pokazalo je prisutnost infekcije u 14 (66,67 %) od 21 ispitane regije Ukrajine. Tijekom ovog razdoblja pojavnost slučajeva PED bila je najniža 2017. godine (1,76 %), a najviša 2016. godine (48,03 %), s progresivnim padom postotka seropozitivnih životinja i seronegativnog indikatora statusa definiranog u krmača 2018. godine. Rezultati određivanja virulencije 40 sojeva PED virusa iz različitih regija Ukrajine uporabom RT- PCR metode dokazali su kruženje vrlo virulentnih sojeva. Filogenetska analiza pokazala je da se endemski soj PED virusa grupirao sa sjevernoameričkim i kineskim sojevima. Potrebno je napomenuti da se nije grupirao s europskim S-INDEL sojevima niske virulentnosti. To navodi na zaključak da je PED virus vrlo vjerojatno unesen u Ukrajinu iz Azije ili SAD-a.