Nonsteroidal anti-inflammatory drug solid-state microencapsulation on green activated carbon : mass transfer and host-guest interactions / Zvezdelina Lyubenova Yaneva.
Sažetak

The present study investigated the drug-carrier capacity of green activated carbon derived from fruit stones by steam-gas activation (ACSTA) towards the nonsteroidal anti-inflammatory drug (NSAID) ibuprofen (IBU), and assessed the host-guest interactions and mass transfer mechanism/s of the drug microencapsulation and in vitro release processes. The mass transfer studies outlined that the process of IBU encapsulation on ACSTA microparticles was predominantly controlled by intraparticle solid phase diffusion.