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Naslov portalaDigitalne zbirke NSK
  
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16.631 (1-10)
Naslov1,2-annulated adamantane heterocyclic derivatives as anti-influenza Α virus agents / Vasiliki Pardali, Erofili Giannakopoulou, Athina Konstantinidi, Antonios Kolocouris, Grigoris Zoidis.
Materijalni opisIlustr.
Način izrade datotekeizvorno digitalna građa
Vrstačlanak
OpisIn this report we review our results on the development of 1,2-annulated adamantane heterocyclic derivatives and we discuss the structure-activity relationships obtained from their biological evaluation against influenza A virus. We have designed and synthesized numerous potent 1,2-annulated adamantane analogues of amantadine and rimantadine against influenza A targeting M2 protein the last 20 years. For their synthesis we utilized the key intermediates 2-(2-oxoadamantan-1-yl)acetic acid and 3-(2-oxoadamantan-1-yl)propanoic acid, which were obtained by a simple, fast and efficient synthetic protocol. The latter involved the treatment of protoadamantanone with different electrophiles and a carbon-skeleton rearrangement. These ketoesters offered a new pathway to the synthesis of 1,2-disubstituted adamantanes, which constitute starting materials for many molecules with pharmacological potential, such as the 1,2-annulated adamantane heterocyclic derivatives. To obtain additional insight for their binding to M2 protein three structurally similar 1,2-annulated adamantane piperidines, differing in nitrogen position, were studied using molecular dynamics (MD) simulations in palmitoyl-oleoyl-phosphatidyl-choline (POPC) hydrated bilayers.
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Naslov1tes Banal Rgmt. No. 10 (1, 3) ; 2tes Banal Gränz Regiment No. 11.
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Naslov2nd International Colloquium on Smart Grid Metrology (SMAGRIMET) : proceedings ; Split, Croatia April 9-12, 2019. / editors Branimir Ivšić, Goran Petrović, Martin Dadić.
ImpresumZagreb : University of Zagreb, Faculty of Electrical Engineering and Computing, 2019.
Materijalni opis1 online jedinica građe (38,5 MB).
Vrsta publikacijeknjigae-knjiga
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Naslov3D planiranje terapije lica : prikaz slučaja = 3D facial treatment planning : case report / Ana Maria Dekanić, Renata Volf, Barbara Mady Maričić, Ruth Munjiza, Robert Cerović.
Materijalni opisIlustr.
Način izrade datotekeizvorno digitalna građa
Vrstačlanak
OpisCilj: Prikazati kako je uporabom suvremenih tehnologija omogućena 3D virtualna priprema i praćenje pacijenta prije, tijekom i nakon zahvata. Prikaz slučaja: Prikazan je pacijent s pravom progenijom, dakle skeletnom klasom III, obrnutim prijeklopom, zbijenošću zuba i konkavnim profilom kojemu su ortodontskom terapijom zuba pripremljeni za ortognatski kirurški zahvat koji je potom izvršen na gornjoj i donjoj čeljusti (LeFort I i BSSO). Dijagnostički postupak i evaluacija ishoda, osim standardnog protokola, uključivao je i pripremu za 3D virtualno planiranje. Učinjeno je skeniranje studijskih modela, CBCT snimak, 3D fotografije i analize pomoću 3D softvera. Kirurške vodilice napravljene su 3D printerom. Zaključak: Korištenjem suvremenih tehnologija i 3D virtualnog planiranja olakšan je i skraćen postupak planiranja ishoda i praćenje rezultata terapije uz veliku preciznost u izradi kirurških vodilica.Aim: Present how contemporary 3D technologies are used to access to 3D virtual treatment planning and evaluation of the patient protocol before, during and after procedures. Case report: Patient with skeletal Class III, negative overjet, crowding and concave profile has been orthodontically prepared for an orthognatic surgery procedure on the upper and lower jaw (LeFort I and BSSO). The diagnostic treatment made by 3D virtual planning includes scanning model casts, CBCT scans, 3D photographies and 3D software. Surgical guides were made with a 3D printer. Conclusion: The use of contemporary technologies for 3D virtual planning of treatment outcome and patient evaluation made the procedure easier and faster with high precision while making surgical guides.
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Naslov3D printing in the apparel sector : how environmentally sustainable is it? / Belinda Carp.
Materijalni opisIlustr.
Način izrade datotekeizvorno digitalna građa
Vrstačlanak
Opis3D printing is a process of making three dimensional (3D) solid objects from a digital file. The object is made using an additive process, which means that successive layers of material are laid down until the object is created. Each of these layers can be seen as a thinly sliced horizontal cross-section of the eventual object. The process enables complex shapes to be produced, using less material than in traditional manufacturing methods.3D printing processes are being used in manufacturing, medicine, architecture, custom art and design. Appli-cations in textiles range from fashion and sportswear to medical devices and aerospace.
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Naslov3D scanner application in the function of digital foot antropometry : (FootSABA 3D Foot Scanner) / Sarajko Baksa, Ines Baksa, Budimir Mijović.
Materijalni opisIlustr., graf. prikazi.
Način izrade datotekeizvorno digitalna građa
Vrstačlanak
OpisThe personalization of footwear in terms of dimension and shape is of the utmost importance and is nowadays considered vitally important by interdisciplinary professions (medical, footwear, ergonomics ...), since inadequately manufactured footwear inevitably results in unwanted pathological conditions of the feet.The aim of this study is to scientifically determine the application of automated 3D digitization of spatial anthropometric foot measurement in relation to the frequency of incorrectly selected footwear based on traditional methods of measurement and selection.Among the examined individuals, both male and female, it was found that more than two thirds of people wear footwear that ergonomically does not fit the basic anthropometric footwear measurements, both in width and length of their feet.There is medical evidence that wearing inappropriate footwear is closely related to pain and wounds on the feet, and that prolonged wearing leads to pathological changes of the feet, such as foot and toe deformation.In the scope of taking measures, traditional methods of determining foot morphology are not sufficient to accurately define the shape and size, in contrast to the modern approach of using 3D scanners and digital methods of measuring virtual 3D models, which enable a very accurate and quick personalization of a large amount of anthropometric data concerning foot morphology.
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Naslov3D-tiskani oralni dozirni oblici punjeni disperzijom ulja i djelatne tvari / Andrea Milićević, Matija Gretić, Gordana Matijašić.
Materijalni opisIlustr.
Način izrade datotekeizvorno digitalna građa
Vrstačlanak
OpisU ovom radu ispitana je mogućnost izrade oralnih dozirnih oblika tehnologijom 3D-tiska. Printani oblici podvrgnuti su in vitro ispitivanju oslobađanja djelatne tvari a rezultati su obrađeni u dodatku za Microsoft Excel, DDSolver. Proizvedeno je šest različitih čvrstih pripravaka. Rezultati ispitivanja oslobađanja djelatne tvari pokazali su profile oslobađanja s početnom vremenskom zadrškom, funkcijski povezanom s debljinom stijenke oblika. Profili su dobro opisani Peppas-Sahlinovim modelom. Pokazano je da tehnologija 3D-tiska ima potencijal postati metodom za jednostavnu i brzu izradu personaliziranih dozirnih oblika s odgođenim oslobađanjem.In this study, the possibility of producing pharmaceutical dosage forms by 3D printing technology is examined. In vitro dissolution tests were performed with printed dosage forms, and the results analysed in Microsoft Excel Add-In, DDSolver. 3D printing has provided six different models of solid dosage forms. The results of dissolution test have shown release profiles with initial time delay. The profiles are described by the Peppas-Sahlin model. It is shown that 3D printing technology has the potential to become a method for quick and simple production of personalized dosage forms with delayed release.
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Naslov3 pjesme na tekstove Vladimira Vidrića / [Branimir Sakač].
Materijalni opis13 str. ; 35 cm.
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16.631 (1-10)